Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5420976 | 0.81 | ACHE (0.35) | ACHEKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL12888375 | 0.77 | TLR7 (0.38) | ACHEKDM4EMEN1MAPK1KMT2A | |
| SCHEMBL6809404 | 0.73 | TLR7 (0.33) | ACHEKDM4EMEN1MAPK1KMT2A | |
| SCHEMBL8113805 | 0.72 | TLR7 (0.39) | ACHEKDM4EMEN1MAPK1KMT2A | |
| SCHEMBL5413387 | 0.72 | TLR7 (0.41) | ACHEKDM4EALDH1A1GAAHPGD | |
| SCHEMBL5415222 | 0.72 | CHRNE (0.34) | ACHEKDM4EMEN1MAPK1KMT2A | |
| SCHEMBL5404740 | 0.71 | TLR7 (0.34) | ACHEKDM4EALDH1A1GAAHPGD | |
| SCHEMBL5409950 | 0.71 | NPSR1 (0.37) | ACHEKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL25575011 | 0.71 | TLR7 (0.46) | — | |
| SCHEMBL4753517 | 0.71 | TLR7 (0.37) | ACHEKDM4EMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006028451-A1 | 1-AMINO 1-H-IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | claimed |
| WO-2006028451-A1 | 1-AMINO 1-H-IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |