Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 13/20 | 0.44 |
| ▸ | MEN1 | O00255 | 10/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.44 |
| ▸ | HPGD | P15428 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 5/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.43 |
| ▸ | LMNA | P02545 | 8/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808242 | 1.00 | P2RX3 (0.45) | P2RX3MAPTMEN1KMT2AHPGD | |
| SCHEMBL5808415 | 0.92 | MAPT (0.43) | MAPTMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL5795610 | 0.83 | P2RX3 (0.51) | P2RX3MAPTMEN1KMT2AHPGD | |
| SCHEMBL5795607 | 0.83 | P2RX3 (0.51) | P2RX3MAPTMEN1KMT2AHPGD | |
| SCHEMBL5807017 | 0.83 | P2RX3 (0.47) | P2RX3MAPTKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL5807019 | 0.83 | P2RX3 (0.47) | P2RX3MAPTKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL5797861 | 0.82 | P2RX3 (0.46) | P2RX3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5797858 | 0.82 | P2RX3 (0.46) | P2RX3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5807110 | 0.82 | P2RX3 (0.49) | P2RX3MAPTMEN1KMT2AHPGD | |
| SCHEMBL5807117 | 0.82 | P2RX3 (0.49) | P2RX3MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | claimed |