Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 4/20 | 0.53 |
| ▸ | CDK1 | P06493 | 4/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.53 |
| ▸ | GSK3B | P49841 | 7/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | PRKCB | P05771 | 3/20 | 0.39 |
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 4/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807760 | 0.90 | CCNB2 (0.53) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL3770147 | 0.81 | CDK1 (0.78) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL5808258 | 0.77 | CDK1 (0.61) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL3775610 | 0.77 | CCNB2 (0.65) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL3775606 | 0.77 | CCNB2 (0.65) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL13239584 | 0.71 | GSK3B (0.77) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL13061452 | 0.70 | CDK1 (0.78) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL3763115 | 0.69 | CDK1 (1.00) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL2539201 | 0.68 | GSK3B (0.66) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL13008036 | 0.68 | CDK1 (0.74) | CCNB2CDK1CCNB1CCNB3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050076-A1 | PYRIMIDINYL SUBSTITUTED FUSED-PYRROLYL COMPOUNDS USEFUL IN TREATING KINASE DISORDERS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-11 | — | — | WO | disclosed |