Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 10/20 | 0.69 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | TACR2 | P21452 | 1/20 | 0.61 |
| ▸ | TACR1 | P25103 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3748189 | 1.00 | TACR3 (0.69) | TACR3TMEM97SIGMAR1TACR2TACR1 | |
| SCHEMBL3741510 | 1.00 | TACR3 (0.69) | TACR3TMEM97SIGMAR1TACR2TACR1 | |
| SCHEMBL5803784 | 0.94 | TACR3 (0.65) | TACR3TACR2TACR1 | |
| SCHEMBL3745701 | 0.94 | TACR3 (0.65) | TACR3TACR2TACR1 | |
| SCHEMBL3743329 | 0.94 | TACR3 (0.65) | TACR3TACR2TACR1 | |
| SCHEMBL3739912 | 0.91 | TACR3 (0.69) | TACR3TACR2TACR1 | |
| SCHEMBL3741220 | 0.91 | TACR3 (0.69) | TACR3TACR2TACR1 | |
| SCHEMBL6024729 | 0.91 | TACR3 (0.69) | TACR3TACR2TACR1 | |
| SCHEMBL3742055 | 0.90 | TMEM97 (0.61) | TACR3TMEM97SIGMAR1 | |
| SCHEMBL3751047 | 0.90 | TACR3 (0.70) | TACR3TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016884-A9 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2006-03-16 | — | — | WO | claimed |