Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 16/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | TACR2 | P21452 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739912 | 1.00 | TACR3 (0.69) | TACR3HTR2CTACR2TACR1 | |
| SCHEMBL3741220 | 1.00 | TACR3 (0.69) | TACR3HTR2CTACR2TACR1 | |
| SCHEMBL3743329 | 0.94 | TACR3 (0.65) | TACR3TACR2TACR1 | |
| SCHEMBL3745701 | 0.94 | TACR3 (0.65) | TACR3TACR2TACR1 | |
| SCHEMBL5803784 | 0.94 | TACR3 (0.65) | TACR3TACR2TACR1 | |
| SCHEMBL3747480 | 0.91 | TACR3 (0.75) | TACR3 | |
| SCHEMBL3736135 | 0.91 | TACR3 (0.75) | TACR3 | |
| SCHEMBL3748189 | 0.91 | TACR3 (0.69) | TACR3TACR2TACR1 | |
| SCHEMBL5808374 | 0.91 | TACR3 (0.69) | TACR3TACR2TACR1 | |
| SCHEMBL3741510 | 0.91 | TACR3 (0.69) | TACR3TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656349-A1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | H. Lundbeck A/S (DK) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005016884-A1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | H. LUNDBECK A/S (DK) | 2005-02-24 | — | — | WO | disclosed |