Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804594 | 0.81 | PRCP (0.35) | — | |
| SCHEMBL6043161 | 0.71 | ACHE (0.48) | TACR1ACHEDRD2DRD4MEN1 | |
| SCHEMBL14261435 | 0.69 | TACR1 (0.47) | TACR1ACHESIGMAR1GRIN1GRIN2B | |
| SCHEMBL14261434 | 0.69 | TACR1 (0.47) | TACR1ACHESIGMAR1GRIN1GRIN2B | |
| SCHEMBL17086759 | 0.68 | SLC18A3 (0.45) | ACHEBCHEBACE1DRD2DRD4 | |
| SCHEMBL17086700 | 0.68 | SLC18A3 (0.45) | ACHEBCHEBACE1DRD2DRD4 | |
| SCHEMBL22795424 | 0.68 | CNR2 (0.60) | ACHEBCHEBACE1DRD2DRD4 | |
| SCHEMBL22778175 | 0.68 | CNR2 (0.60) | ACHEBCHEBACE1DRD2DRD4 | |
| SCHEMBL22795433 | 0.68 | CNR2 (0.60) | ACHEBCHEBACE1DRD2DRD4 | |
| SCHEMBL6042407 | 0.68 | ABCB1 (0.46) | TACR1ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006089038-A2 | INSECTICIDAL TETRAHYDROINDENOPYRIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-08-24 | — | — | WO | disclosed |