Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808775 | 0.75 | KDM4E (0.43) | MAPTKMT2APOLBNPC1SMN1; SMN2 | |
| SCHEMBL5812057 | 0.74 | GRM5 (0.46) | MAPTKMT2APOLBNPC1RAB9A | |
| SCHEMBL1738226 | 0.72 | CYP1A2 (0.47) | MAPTKMT2ARAB9AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL1736478 | 0.71 | CYP1A2 (0.46) | MAPTKMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL1738348 | 0.71 | CYP1A2 (0.38) | MAPTKMT2AMEN1KDM4ECDK2 | |
| Hydrochloric Acid SCHEMBL1737586 | 0.70 | CYP1A2 (0.38) | MAPTKDM4ECDK2 | |
| SCHEMBL1737859 | 0.70 | BCHE (0.58) | MAPTALDH1A1KDM4ECDK2 | |
| SCHEMBL1735327 | 0.69 | CYP1A2 (0.39) | MAPTALDH1A1KDM4ECDK2 | |
| Hydrochloric Acid SCHEMBL1739555 | 0.68 | CYP1A2 (0.39) | MAPTALDH1A1KDM4ECDK2 | |
| SCHEMBL1738966 | 0.68 | CYP1A2 (0.36) | MAPTKMT2APOLBMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |