Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808489 | 0.75 | MAPT (0.53) | KDM4EMAPTALDH1A1THRBNPC1 | |
| SCHEMBL933660 | 0.72 | BCHE (0.60) | KDM4EMAPTCYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL1737822 | 0.72 | MAPT (0.47) | KDM4EMAPTCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL5810355 | 0.71 | MAPT (0.44) | KDM4EMAPTCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL29951565 | 0.71 | MAPT (0.44) | KDM4EMAPTCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL2474644 | 0.71 | CYP1A2 (0.50) | MAPTCYP3A4CYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL6239184 | 0.71 | BCHE (0.59) | KDM4EMAPTCYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL1735558 | 0.70 | TDO2 (0.59) | KDM4EMAPTCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL29894114 | 0.70 | CYP19A1 (0.48) | KDM4EMAPTCYP3A4ALDH1A1DYRK1A | |
| SCHEMBL5806332 | 0.69 | KDM4E (0.45) | KDM4EMAPTCYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |