Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 3/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246294 | 0.85 | MAPK11 (0.55) | MAPK13MAPK11CYP2C9HPGDALDH1A1 | |
| SCHEMBL5812295 | 0.84 | MAPK13 (0.53) | MAPK13MAPK11CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL5806880 | 0.84 | MAPK13 (0.50) | MAPK13MAPK11CYP2C9HPGDLMNA | |
| SCHEMBL5811657 | 0.84 | MAPK11 (0.54) | MAPK13MAPK11CYP2C9ALDH1A1KDM4E | |
| SCHEMBL4240989 | 0.82 | MAPK13 (0.50) | MAPK13MAPK11CYP2C9CNR1MAPK12 | |
| SCHEMBL4241311 | 0.81 | MAPK13 (0.51) | MAPK13MAPK11CYP2C9CNR1MAPK12 | |
| SCHEMBL4240672 | 0.81 | MAPK13 (0.48) | MAPK13MAPK11CYP2C9MAPK12MAPK14 | |
| SCHEMBL4245202 | 0.79 | MAPK13 (0.53) | MAPK13MAPK11CYP2C9ALDH1A1KDM4E | |
| SCHEMBL4245986 | 0.79 | MAPK13 (0.53) | MAPK13MAPK11CYP2C9ALDH1A1KDM4E | |
| SCHEMBL4243633 | 0.79 | MAPK13 (0.49) | MAPK13MAPK11CYP2C9ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038734-A1 | PYRIDAZINONE DERIVATIVES CYTOKINES INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2006-04-13 | — | — | WO | disclosed |