Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808903 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRHIF1ACYP1A2MEN1 | |
| SCHEMBL1081382 | 0.77 | LMNA (0.38) | TSHRCYP1A2MEN1TP53KMT2A | |
| SCHEMBL15950909 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRHIF1ACYP1A2MEN1 | |
| Kinetin SCHEMBL29829493 | 0.74 | SMN1; SMN2 (0.66) | SMN1; SMN2TSHRHIF1ACYP1A2MEN1 | |
| Kinetin SCHEMBL15705 | 0.74 | SMN1; SMN2 (0.66) | SMN1; SMN2TSHRHIF1ACYP1A2MEN1 | |
| SCHEMBL17009436 | 0.74 | GAA (0.43) | SMN1; SMN2TSHRHIF1ACYP1A2MEN1 | |
| SCHEMBL19958904 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRHIF1ACYP1A2MEN1 | |
| SCHEMBL19064637 | 0.73 | SMN1; SMN2 (0.51) | SMN1; SMN2TSHRHIF1ACYP1A2MEN1 | |
| SCHEMBL15950879 | 0.71 | MAPT (0.51) | TSHRHIF1ACYP1A2MEN1TP53 | |
| SCHEMBL17009422 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRHIF1ACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006061627-A2 | ANTIAGING COMPOSITION | OXONICA LTD (GB) | 2006-06-15 | — | — | WO | disclosed |