Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821883 | 0.77 | EGFR (0.51) | PIM1EGFRMEN1KMT2AMAPT | |
| SCHEMBL5807302 | 0.76 | PDE4A (0.48) | PIM1PREPMEN1KMT2AMAPT | |
| SCHEMBL5816765 | 0.76 | PDE4A (0.48) | PIM1PREPMEN1KMT2AMAPT | |
| SCHEMBL13183079 | 0.75 | MAPT (0.61) | PIM1EGFRMEN1KMT2AMAPT | |
| SCHEMBL5811855 | 0.72 | KDM4E (0.65) | PIM1PREPMEN1KMT2AMAPT | |
| SCHEMBL5821938 | 0.71 | HTT (0.50) | MEN1KMT2AMAPTPDE4DKDM4E | |
| SCHEMBL11689685 | 0.71 | EGFR (0.68) | PIM1EGFRMEN1KMT2AMAPT | |
| SCHEMBL5821557 | 0.70 | PIM1 (0.54) | PIM1EGFRPREPMEN1KMT2A | |
| SCHEMBL11526641 | 0.70 | PIM1 (0.69) | PIM1EGFRMEN1KMT2AMAPT | |
| SCHEMBL5817030 | 0.69 | PIM1 (0.49) | PIM1PREPMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006107827-A1 | SKIN BONDING PROCESS | CREIGHTON UNIVERSITY (US) | 2006-10-12 | — | — | WO | disclosed |