SCHEMBL580901

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10217412	0.83	FLT1 (0.60)	NPSR1HTTLMNAPRNPCYP1A2
	SCHEMBL580885	0.81	KDR (0.62)	NPSR1HTTLMNAMAPTKDR
	SCHEMBL10217415	0.78	MEN1 (0.47)	NPSR1HTTLMNAPRNPCYP1A2
	SCHEMBL28139644	0.77	GAA (0.68)	NPSR1HTTLMNACYP1A2CYP2C9
	SCHEMBL10217403	0.76	MEN1 (0.61)	NPSR1HTTLMNAPRNPCYP1A2
	SCHEMBL4864061	0.73	HTT (0.60)	NPSR1HTTLMNACYP1A2CYP3A4
	SCHEMBL24733360	0.73	NPSR1 (0.56)	NPSR1HTTLMNAPRNPCYP1A2
	SCHEMBL15761431	0.72	PDE4A (0.41)	NPSR1HTTLMNAPRNPCYP1A2
	SCHEMBL13911024	0.71	HTT (0.54)	NPSR1HTTLMNACYP1A2CYP3A4
	Biphenyl SCHEMBL8082690	0.71	ESR1 (0.70)	HTTLMNACYP3A4METGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.