Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TTK | P33981 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457926 | 0.95 | HTT (0.56) | HTTLMNAALDH1A1NPSR1MAPT | |
| SCHEMBL13911030 | 0.92 | HTT (0.54) | HTTLMNAALDH1A1NPSR1MAPT | |
| SCHEMBL13911024 | 0.92 | HTT (0.54) | HTTLMNAALDH1A1NPSR1MAPT | |
| SCHEMBL13911027 | 0.88 | HTT (0.50) | HTTLMNAALDH1A1NPSR1MAPT | |
| SCHEMBL580414 | 0.86 | MAPT (0.49) | HTTLMNAALDH1A1NPSR1MAPT | |
| SCHEMBL7664718 | 0.86 | NPSR1 (0.49) | HTTLMNAALDH1A1NPSR1MAPT | |
| SCHEMBL7657206 | 0.86 | HTT (0.48) | HTTLMNAALDH1A1NPSR1MAPT | |
| SCHEMBL31132418 | 0.86 | KDM4E (0.65) | HTTLMNAALDH1A1NPSR1MAPT | |
| SCHEMBL219856 | 0.86 | KDM4E (0.65) | HTTLMNAALDH1A1NPSR1MAPT | |
| SCHEMBL7068103 | 0.86 | ALDH1A1 (0.53) | HTTLMNAALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180123054-A1 | COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND LIGHTING | MITSUBISHI CHEMICAL CORPORATION (JP) | 2018-05-03 | — | — | US | disclosed |
| US-20180123054-A1 | COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND LIGHTING | MITSUBISHI CHEMICAL CORPORATION (JP) | 2018-05-03 | — | — | US | disclosed |
| US-9899606-B2 | Composition for organic electroluminescent element, organic electroluminescent element, display and lighting | MITSUBISHI CHEMICAL CORPORATION (JP) | 2018-02-20 | — | — | US | disclosed |
| US-9899606-B2 | Composition for organic electroluminescent element, organic electroluminescent element, display and lighting | MITSUBISHI CHEMICAL CORPORATION (JP) | 2018-02-20 | — | — | US | disclosed |
| US-9525009-B2 | Organic electroluminescent element and organic electroluminescent device | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-12-20 | — | — | US | disclosed |
| US-9525009-B2 | Organic electroluminescent element and organic electroluminescent device | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-12-20 | — | — | US | disclosed |
| US-20160043325-A1 | COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND LIGHTING | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| US-20160043325-A1 | COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND LIGHTING | MITSUBISHI CHEMICAL CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| US-20140246660-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT DEVICE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2014-09-04 | — | — | US | disclosed |
| US-20140246660-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT DEVICE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2014-09-04 | — | — | US | disclosed |
| EP-2168576-A2 | New utilities of tricyclic compounds | Shionogi & Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-20080318958-A1 | New utilities of tricyclic compounds | ISHIZUKA NATSUKI | 2008-12-25 | — | — | US | disclosed |
| US-20080318958-A1 | New utilities of tricyclic compounds | ISHIZUKA NATSUKI | 2008-12-25 | — | — | US | disclosed |
| US-7429662-B2 | Red-emitting electrophosphorescent devices | CITY UNIVERSITY OF HONG KONG (CN) | 2008-09-30 | — | — | US | disclosed |
| US-20060261730-A1 | Red-emitting electrophosphorescent devices | CITY UNIVERSITY OF HONG KONG (CN) | 2006-11-23 | — | — | US | disclosed |
| US-6057473-A | Synthesis of aryl serines | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-05-02 | — | — | US | disclosed |
| US-5767304-A | USING OSMIUM CATALYST AND CHIRAL LIGAND | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-16 | — | — | US | disclosed |
| WO-1997046516-A1 | CATALYTIC ASYMMETRIC AMINOHYDROXYLATION OF OLEFINS WITH CARBAMATES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318958-A1 | New utilities of tricyclic compounds | APOB, PON1, APOL1 | HTT 1533/4885LMNA 920/4885ALDH1A1 934/4885 |
| US-20060261730-A1 | Red-emitting electrophosphorescent devices | IK, EED, SPR | HTT 3692/4885LMNA 4569/4885ALDH1A1 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.