Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | CDC25B | P30305 | 5/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.36 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410951 | 0.79 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL1599203 | 0.77 | MAPK10 (0.47) | MAPK10MAPK9 | |
| SCHEMBL4571044 | 0.75 | MAPK14 (0.80) | MAPK14 | |
| SCHEMBL5806276 | 0.73 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL5810394 | 0.70 | EGFR (0.36) | GAKRIPK2COQ8ANLKS1PR1 | |
| SCHEMBL5198985 | 0.68 | TAAR1 (0.49) | HTTAURKA | |
| SCHEMBL1600197 | 0.67 | MAPK8 (0.48) | MAPK14MAPK10MAPK8AURKA | |
| SCHEMBL1600714 | 0.67 | MAPK8 (0.40) | MAPK14MAPK8AURKA | |
| SCHEMBL1600050 | 0.66 | IDO1 (0.46) | CDC25B | |
| SCHEMBL9290332 | 0.64 | PLK1 (0.41) | CDC25BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006091862-A2 | CYTOKINE INHIBITORS AND THEIR USE IN THERAPY | KEMIA, INC. (US) | 2006-08-31 | — | — | WO | disclosed |