SCHEMBL5809113

SCHEMBL5809113

Cc1cc(C(C)(C)C)cc(-n2nc3ccc(Cl)cc3n2)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.45
RAB9A P51151 5/20 0.45
KMT2A Q03164 5/20 0.37
MEN1 O00255 4/20 0.37
ATM Q13315 3/20 0.37
MAPT P10636 3/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 2/20 0.35
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TP53 P04637 2/20 0.32
HCAR1 Q9BXC0 1/20 0.32
CHEK1 O14757 1/20 0.32
LIMK1 P53667 1/20 0.32
MAPK14 Q16539 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
ALOX5 P09917 1/20 0.32
PTGS1 P23219 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29814540 1.00 NPC1 (0.45) NPC1RAB9AKMT2AMEN1ATM
SCHEMBL29349567 0.88 NPC1 (0.41) NPC1RAB9AKMT2AMEN1ATM
SCHEMBL29241 0.88 NPC1 (0.41) NPC1RAB9AKMT2AMEN1ATM
SCHEMBL20591060 0.87 NPC1 (0.40) NPC1RAB9AKMT2AMEN1ATM
SCHEMBL9408759 0.87 NPC1 (0.40) NPC1RAB9AKMT2AMEN1ATM
SCHEMBL11352190 0.86 NPC1 (0.46) NPC1RAB9AKMT2AMEN1ATM
SCHEMBL20592414 0.86 NPC1 (0.39) NPC1RAB9AKMT2AMEN1ATM
SCHEMBL28583461 0.85 NPC1 (0.44) NPC1RAB9AKMT2AMEN1ATM
Bumetrizole SCHEMBL5194149 0.85 NPC1 (0.48) NPC1RAB9AATMMAPTKDM4E
SCHEMBL19119905 0.85 NPC1 (0.39) NPC1RAB9AATMMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11655323-B2 Poly(amide-imide) copolymer film and method for preparing same LG CHEM, LTD. (KR) 2023-05-23 US disclosed
CN-110914345-B Poly (amide-imide) copolymer film and method of making the same 株式会社LG化学 2022-07-26 CN disclosed
US-20200369816-A1 POLY(AMIDE-IMIDE) COPOLYMER FILM AND METHOD FOR PREPARING SAME LG CHEM, LTD. (KR) 2020-11-26 US disclosed
EP-3640286-A1 AROMATIC POLY(AMIDE-IMIDE) COPOLYMER FILM AND PRODUCTION METHOD THEREFOR LG CHEM, LTD. (KR) 2020-04-22 EP disclosed
CN-110914345-A Poly (amide-imide) copolymer film and method of making the same 株式会社LG化学 2020-03-24 CN disclosed
WO-2006120218-A1 IMPROVED METHOD FOR REMOVAL OF RESIDUAL MONOMER FROM POLYOXYMETHYLENES BASF AKTIENGESELLSCHAFT (DE) 2006-11-16 WO disclosed
WO-2006120199-A1 USE OF POLYETHYLENE IMINES FOR REDUCING THE RESIDUAL FORMALDEHYDE CONTENT OF POLYOXYMETHYLENES BASF AKTIENGESELLSCHAFT (DE) 2006-11-16 WO disclosed
WO-2006089915-A1 METHOD FOR PRODUCING FORMALDEHYDE-POOR POLYOXYMETHYLEN BASF AKTIENGESELLSCHAFT (DE) 2006-08-31 WO disclosed