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Sugi Predict / Compounds / SCHEMBL5809162

SCHEMBL5809162

SCHEMBL5809162

CC(C)(C)OC(=O)N1CCN(c2ccc(N3CC(COc4cccnc4)OC3=O)cc2F)CC1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 8/20 0.49
▸ MAOA P21397 5/20 0.49
▸ GPR119 Q8TDV5 4/20 0.46
▸ CALML3 P27482 2/20 0.46
▸ LMNA P02545 1/20 0.46
▸ PTGS1 P23219 1/20 0.46
▸ SDHA P31040 1/20 0.46
▸ CYP3A4 P08684 1/20 0.43
▸ CYP2D6 P10635 1/20 0.43
▸ GRM2 Q14416 1/20 0.43
▸ F10 P00742 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5812809 0.91 MAOB (0.52) MAOBMAOAGPR119CALML3LMNA
SCHEMBL5814121 0.88 MAOB (0.50) MAOBMAOAGPR119CALML3LMNA
SCHEMBL6111262 0.84 MAOB (0.59) MAOBMAOACALML3LMNAPTGS1
SCHEMBL6613535 0.84 MAOB (0.59) MAOBMAOACALML3LMNAPTGS1
SCHEMBL2948879 0.84 MAOB (0.59) MAOBMAOACALML3LMNAPTGS1
SCHEMBL5810297 0.83 MAOB (0.58) MAOBMAOACALML3LMNAPTGS1
SCHEMBL7082597 0.83 MAOB (0.53) MAOBMAOACALML3LMNAPTGS1
SCHEMBL6111117 0.83 MAOB (0.53) MAOBMAOACALML3LMNAPTGS1
SCHEMBL80077 0.82 MAOB (0.58) MAOBMAOACALML3LMNAPTGS1
SCHEMBL3396418 0.82 MAOB (0.58) MAOBMAOACALML3LMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006043121-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-27 — — WO disclosed