SCHEMBL3396418

SCHEMBL3396418

CC(C)(C)OC(=O)N1CCN(c2ccc(N3CC(CN)OC3=O)cc2F)CC1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 11/20 0.58
MAOA P21397 6/20 0.58
LMNA P02545 1/20 0.54
PTGS1 P23219 1/20 0.54
CALML3 P27482 1/20 0.54
SDHA P31040 1/20 0.54
F10 P00742 8/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80077 1.00 MAOB (0.58) MAOBMAOALMNAPTGS1CALML3
SCHEMBL2948879 0.91 MAOB (0.59) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6111262 0.91 MAOB (0.59) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6613535 0.91 MAOB (0.59) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13174832 0.89 MAOB (0.55) MAOBMAOALMNAPTGS1CALML3
SCHEMBL2480376 0.89 MAOA (0.48) MAOBMAOALMNAPTGS1CALML3
SCHEMBL18059593 0.89 MAOA (0.48) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5810297 0.88 MAOB (0.58) MAOBMAOALMNAPTGS1CALML3
SCHEMBL5412271 0.88 MAOB (0.56) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13271873 0.88 MAOB (0.49) MAOBMAOALMNAPTGS1CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100234390-A1 NOVEL COMPOUND AND THEIR USE ORCHID RESEARCH LABORATORIES LIMITED (IN) 2010-09-16 US disclosed
EP-0640077-B1 OXAZOLIDINONES CONTAINING A SUBSTITUTED DIAZINE MOIETY AND THEIR USE AS ANTIMICROBIALS UPJOHN CO (US) 2002-06-26 EP disclosed
CN-1044236-C Oxazolidinone antimicrobials containing substituted diazine moieties PHARMACIA UPJOHN CO (US) 1999-07-21 CN disclosed
US-5700799-A MICROBIOCIDES FOR TREATING HUMAN OR ANIMAL DISEASES PHARMACIA & UPJOHN COMPANY (US) 1997-12-23 US disclosed
US-5547950-A FOR TREATING DRUG RESISTANT STAPHYLOCOCCUS AND STREPTOCOCCUS INFECTIONS THE UPJOHN COMPANY (US) 1996-08-20 US disclosed
EP-0640077-A1 OXAZOLIDINONES CONTAINING A SUBSTITUTED DIAZINE MOIETY AND THEIR USE AS ANTIMICROBIALS PHARMACIA & UPJOHN COMPANY (US) 1995-03-01 EP disclosed
WO-1993023384-A1 OXAZOLIDINONES CONTAINING A SUBSTITUTED DIAZINE MOIETY AND THEIR USE AS ANTIMICROBIALS THE UPJOHN COMPANY (US) 1993-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234390-A1 NOVEL COMPOUND AND THEIR USE HTRA1, PRSS1, PRNP MAOB 2054/4885MAOA 2174/4885LMNA 2167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.