Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16543214 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHRTP53CYP3A4MAPK1 | |
| SCHEMBL27714950 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TET2TGFBR1EGLN1 | |
| SCHEMBL2535053 | 0.74 | TSHR (0.40) | ALDH1A1HCAR2TSHRTP53CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL29164923 | 0.73 | TET2 (0.38) | ALDH1A1TET2TGFBR1EGLN1KEAP1 | |
| SCHEMBL1899520 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TET2EGLN1 | |
| SCHEMBL3726540 | 0.71 | — | — | |
| SCHEMBL9286079 | 0.71 | CYP3A4 (0.37) | ALDH1A1TSHRTP53CYP3A4MAPK1 | |
| SCHEMBL219777 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TET2EGLN1 | |
| SCHEMBL16881862 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TET2EGLN1TSHR | |
| SCHEMBL9745781 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TET2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006072613-A2 | PREPARATION COMPRISING MICROPARTICLES OF AN INSOLUBLE POLYSACCHARIDE RESIN WITH A BIOPOLYMERIC ACTIVE INGREDIENT AND METHOD FOR PRODUCTION THEREOF | RUIZ, JEAN-MARC (FR) | 2006-07-13 | — | — | WO | disclosed |