SCHEMBL5809246

SCHEMBL5809246

Cc1[nH]c2c(OCC3CCCC3)nccc2c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
CDK2 P24941 11/20 0.42
CDK1 P06493 8/20 0.42
CCNA2 P20248 10/20 0.41
CCNB1 P14635 7/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
FFAR2 O15552 3/20 0.39
KDM4C Q9H3R0 1/20 0.39
CHUK O15111 1/20 0.38
CCNA1 P78396 3/20 0.38
CCNB2 O95067 2/20 0.38
CCNB3 Q8WWL7 2/20 0.38
MAPK3 P27361 1/20 0.37
CLK1 P49759 1/20 0.37
CDK5 Q00535 1/20 0.37
PIN1 Q13526 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5810274 0.99 MAOA (0.47) MAOAMAOBCDK2CDK1CCNA2
SCHEMBL5805827 0.81 POLB (0.46) CYP1A2CYP3A4CYP2C9CYP2C19FFAR2
Hydrochloric Acid SCHEMBL5809046 0.80 POLB (0.45) CYP1A2CYP3A4CYP2C9CYP2C19FFAR2
SCHEMBL5806332 0.75 KDM4E (0.45) MAOACDK2CDK1CCNA2CCNB1
Hydrochloric Acid SCHEMBL5806237 0.73 MAOA (0.44) MAOACDK2CDK1CCNA2CCNB1
Hydrochloric Acid SCHEMBL5808609 0.73 KDM4E (0.44) MAOACDK2CDK1CCNA2CCNB1
SCHEMBL5811682 0.72 MAOA (0.47) MAOACDK2CDK1CCNA2CCNB1
SCHEMBL5806110 0.72 CYP1A2 (0.41) MAOACDK2CDK1CCNA2CCNB1
SCHEMBL5808715 0.71 CYP1A2 (0.40) MAOACYP1A2CYP3A4CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL5806423 0.71 CYP1A2 (0.40) MAOACDK2CDK1CCNA2CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO claimed
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO disclosed