Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600507 | 0.89 | CNR1 (0.61) | CNR1CNR2POLBMAPK14KDM4E | |
| SCHEMBL12705468 | 0.86 | CNR1 (0.58) | CNR1CNR2POLBMAPK14KDM4E | |
| SCHEMBL1600234 | 0.86 | MAPK14 (0.59) | CNR1CNR2POLBMAPK14KDM4E | |
| SCHEMBL6260918 | 0.84 | CNR1 (0.64) | CNR1CNR2POLBMAPK14KDM4E | |
| SCHEMBL2788546 | 0.84 | CNR1 (0.57) | CNR1CNR2POLBMAPK14KDM4E | |
| SCHEMBL2788543 | 0.83 | CNR1 (0.72) | CNR1CNR2POLBMAPK14KDM4E | |
| SCHEMBL4566793 | 0.81 | MAPK14 (0.66) | CNR1CNR2MAPK14MAPK13MAPK12 | |
| SCHEMBL30009966 | 0.81 | MAPK14 (0.66) | CNR1CNR2MAPK14MAPK13MAPK12 | |
| SCHEMBL4953382 | 0.81 | CNR1 (0.69) | CNR1CNR2POLBMAPK14KDM4E | |
| SCHEMBL5805878 | 0.81 | POLB (0.46) | CNR1CNR2POLBKDM4EDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006091862-A2 | CYTOKINE INHIBITORS AND THEIR USE IN THERAPY | KEMIA, INC. (US) | 2006-08-31 | — | — | WO | disclosed |