Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925065 | 1.00 | MAPT (0.54) | MAPTRXFP1S1PR1S1PR3S1PR2 | |
| SCHEMBL10925462 | 0.97 | MAPT (0.50) | MAPTRXFP1S1PR1S1PR3S1PR2 | |
| SCHEMBL2835656 | 0.87 | MAPT (0.69) | MAPTRXFP1S1PR1S1PR3S1PR2 | |
| SCHEMBL25575670 | 0.87 | MAPT (0.69) | MAPTRXFP1S1PR1S1PR3S1PR2 | |
| Iocanlidic Acid SCHEMBL290025 | 0.87 | MAPT (0.69) | MAPTRXFP1S1PR1S1PR3S1PR2 | |
| SCHEMBL9860436 | 0.87 | MAPT (0.69) | MAPTRXFP1S1PR1S1PR3S1PR2 | |
| SCHEMBL5033209 | 0.87 | S1PR2 (0.50) | S1PR1S1PR3S1PR2ALB | |
| Iodofiltic Acid SCHEMBL4422554 | 0.87 | S1PR2 (0.50) | S1PR1S1PR3S1PR2ALB | |
| Iodofiltic Acid SCHEMBL4422557 | 0.87 | S1PR2 (0.50) | S1PR1S1PR3S1PR2ALB | |
| Iodofiltic Acid SCHEMBL289760 | 0.87 | S1PR2 (0.50) | S1PR1S1PR3S1PR2ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004321-B1 | STABLE RADIOACTIVE MEDECINE | DAIICHI RADIOISOTOPE LAB (JP) | 2003-02-26 | — | — | EP | claimed |
| EP-0153403-A4 | CHEMICAL COMPOUNDS. | MALLINCKRODT INC (US) | 1985-12-11 | — | — | EP | claimed |
| EP-0153403-A1 | CHEMICAL COMPOUNDS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1985-09-04 | — | — | EP | claimed |
| WO-1985000753-A1 | CHEMICAL COMPOUNDS | MALLINCKRODT, INC. (US) | 1985-02-28 | — | — | WO | claimed |
| WO-2006117945-A1 | METHOD FOR DETECTING LIPID METABOLISM DISORDER, AND DIAGNOSTIC AGENT FOR USE THEREIN | KOCHI UNIVERSITY (JP) | 2006-11-09 | — | — | WO | disclosed |
| EP-1004321-B1 | STABLE RADIOACTIVE MEDECINE | DAIICHI RADIOISOTOPE LAB (JP) | 2003-02-26 | — | — | EP | disclosed |
| EP-1004321-A1 | STABLE RADIOACTIVE MEDECINE | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2000-05-31 | — | — | EP | disclosed |
| EP-0153403-A4 | CHEMICAL COMPOUNDS. | MALLINCKRODT INC (US) | 1985-12-11 | — | — | EP | disclosed |
| EP-0153403-A4 | CHEMICAL COMPOUNDS. | MALLINCKRODT INC (US) | 1985-12-11 | — | — | EP | disclosed |
| EP-0153403-A1 | CHEMICAL COMPOUNDS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1985-09-04 | — | — | EP | disclosed |
| EP-0153403-A1 | CHEMICAL COMPOUNDS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1985-09-04 | — | — | EP | disclosed |
| WO-1985000753-A1 | CHEMICAL COMPOUNDS | MALLINCKRODT, INC. (US) | 1985-02-28 | — | — | WO | disclosed |
| WO-1985000753-A1 | CHEMICAL COMPOUNDS | MALLINCKRODT, INC. (US) | 1985-02-28 | — | — | WO | disclosed |