Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19665221 | 0.83 | HPGD (1.00) | HPGDALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL8380313 | 0.81 | HPGD (0.65) | HPGDALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL7496014 | 0.78 | POLB (0.72) | HPGDALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL5784174 | 0.77 | HPGD (0.47) | HPGDALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL4142417 | 0.75 | HTT (0.50) | HPGDALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL1162891 | 0.74 | HPGD (0.80) | HPGDALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL19665220 | 0.73 | HPGD (0.59) | HPGDALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL20570670 | 0.73 | HPGD (0.79) | HPGDALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL26847401 | 0.72 | HPGD (0.56) | HPGDALDH1A1CYP1A2CYP2C9MEN1 | |
| SCHEMBL13851751 | 0.72 | PDE5A (0.55) | HPGDALDH1A1CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100095-A1 | SUBSTITUTED CARBOXAMIDES METHOD FOR PRODUCTION AND USE THEREOF AS TNF-ALPHA RELEASE INHIBITORS | CURACYTE DISCOVERY GMBH (DE) | 2006-09-28 | — | — | WO | disclosed |