Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347394 | 0.82 | KMT2A (0.61) | HPGDALDH1A1CYP1A2CYP2C9RXFP1 | |
| SCHEMBL5809667 | 0.81 | HPGD (0.70) | HPGDALDH1A1CYP1A2CYP2C9RXFP1 | |
| SCHEMBL19665221 | 0.79 | HPGD (1.00) | HPGDALDH1A1CYP1A2CYP2C9RXFP1 | |
| SCHEMBL213872 | 0.77 | GAA (0.57) | HPGDALDH1A1CYP2C9RXFP1PPARG | |
| SCHEMBL10271853 | 0.77 | GAA (0.70) | HPGDALDH1A1RXFP1PPARGNCOR2 | |
| SCHEMBL16772576 | 0.75 | RXFP1 (0.95) | HPGDALDH1A1CYP1A2CYP2C9RXFP1 | |
| SCHEMBL7901099 | 0.74 | MAPT (0.48) | HPGDALDH1A1CYP1A2CYP2C9RXFP1 | |
| SCHEMBL10466353 | 0.73 | GAA (1.00) | HPGDALDH1A1RXFP1PPARGNCOR2 | |
| SCHEMBL15448702 | 0.71 | RXFP1 (0.52) | HPGDALDH1A1CYP1A2CYP2C9RXFP1 | |
| SCHEMBL9543700 | 0.71 | SMN1; SMN2 (0.64) | HPGDALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221103-A1 | New heterocyclic compounds | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221103-A1 | New heterocyclic compounds | LOXL4, CXCR4, LTC4S | HPGD 1364/4885ALDH1A1 825/4885CYP1A2 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.