Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813244 | 0.88 | PTGS2 (0.60) | PTGS2PTGS1HRH4 | |
| SCHEMBL5813218 | 0.87 | PTGS2 (0.54) | PTGS2PTGS1HRH4 | |
| SCHEMBL5553683 | 0.86 | PTGS2 (0.66) | PTGS2PTGS1HRH4 | |
| SCHEMBL5558243 | 0.86 | PTGS2 (0.66) | PTGS2PTGS1HRH4 | |
| SCHEMBL5812264 | 0.86 | PTGS2 (0.51) | PTGS2PTGS1HRH4 | |
| SCHEMBL5808118 | 0.85 | PTGS2 (0.51) | PTGS2PTGS1HRH4 | |
| SCHEMBL5808445 | 0.85 | PTGS2 (0.57) | PTGS2PTGS1HRH4 | |
| SCHEMBL5813929 | 0.85 | PTGS2 (0.51) | PTGS2PTGS1HRH4 | |
| SCHEMBL6426776 | 0.85 | PTGS2 (0.63) | PTGS2PTGS1HRH4 | |
| SCHEMBL5554433 | 0.85 | PTGS2 (0.63) | PTGS2PTGS1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |