Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 7/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810799 | 1.00 | TLR8 (0.39) | TLR8TLR7NUDT1MAPTALDH1A1 | |
| SCHEMBL4756669 | 0.87 | TLR7 (0.37) | TLR8TLR7NUDT1MAPTALDH1A1 | |
| SCHEMBL4756665 | 0.87 | TLR7 (0.37) | TLR8TLR7NUDT1MAPTALDH1A1 | |
| SCHEMBL4790061 | 0.85 | ALDH1A1 (0.46) | TLR8TLR7NUDT1MAPTALDH1A1 | |
| SCHEMBL5447365 | 0.85 | ALDH1A1 (0.46) | TLR8TLR7NUDT1MAPTALDH1A1 | |
| SCHEMBL4755381 | 0.85 | TLR7 (0.39) | TLR8TLR7NUDT1MAPTALDH1A1 | |
| SCHEMBL4758684 | 0.83 | ALDH1A1 (0.56) | TLR8TLR7MAPTALDH1A1RAB9A | |
| SCHEMBL4758685 | 0.83 | ALDH1A1 (0.56) | TLR8TLR7MAPTALDH1A1RAB9A | |
| SCHEMBL4755190 | 0.81 | TLR7 (0.39) | TLR8TLR7NUDT1MAPTALDH1A1 | |
| SCHEMBL4755191 | 0.81 | TLR7 (0.39) | TLR8TLR7NUDT1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006028451-A1 | 1-AMINO 1-H-IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |