Piperidine

Piperidine

SCHEMBL5811153

C1CCNCC1.NN

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperidine SCHEMBL27335664 0.96
SCHEMBL6890150 0.91 ALDH1A1 (1.00)
SCHEMBL11508384 0.91 ALDH1A1 (1.00)
SCHEMBL3071895 0.91 ALDH1A1 (1.00)
SCHEMBL3069642 0.91 ALDH1A1 (1.00)
SCHEMBL8253733 0.91 ALDH1A1 (1.00)
Piperidine SCHEMBL11283826 0.91
SCHEMBL21753221 0.91 ALDH1A1 (1.00)
Piperidine SCHEMBL21819962 0.91 ALDH1A1 (1.00)
Azepane SCHEMBL11361504 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970291-B1 PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT JANSSEN PHARMACEUTICA NV (BE) 2022-05-11 EP disclosed
CN-112608298-A Process and intermediates for the preparation of a medicament 詹森药业有限公司 2021-04-06 CN disclosed
US-20200181709-A1 METHODS OF DETECTION AND TREATMENT OF UROTHELIAL CANCER THE JOHNS HOPKINS UNIVERSITY 2020-06-11 US disclosed
US-10435383-B2 C-glycoside derivatives OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2019-10-08 US disclosed
EP-2888268-B1 NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) 2018-08-22 EP disclosed
US-20180118703-A1 C-GLYCOSIDE DERIVATIVES OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2018-05-03 US disclosed
CN-104995194-B Spirocyclic indole derivatives and process for preparing the same 学校法人冲绳科学技术大学院大学学园 2017-08-29 CN disclosed
WO-2016205236-A1 METHODS OF DETECTION AND TREATMENT OF UROTHELIAL CANCER THE JOHNS HOPKINS UNIVERSITY (US) 2016-12-22 WO disclosed
WO-2016151989-A1 C-GLYCOSIDE DERIVATIVES OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2016-09-29 WO disclosed
US-9309261-B2 Spirooxindole derivative and process for producing the same OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2016-04-12 US disclosed
EP-2970291-A1 PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT Janssen Pharmaceutica, N.V. (BE) 2016-01-20 EP disclosed
CN-105026400-A Process and intermediates for the preparation of a medicament JANSSEN PHARMACEUTICA NV 2015-11-04 CN disclosed
CN-104995194-A Novel spirocyclic indole derivatives and process for preparing same OKINAWA INST OF SCIENCE AND TECHNOLOGY SCHOOL CORP 2015-10-21 CN disclosed
US-20150246927-A1 NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2015-09-03 US disclosed
EP-2888268-A1 NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME Okinawa Institute of Science and Technology School Corporation (JP) 2015-07-01 EP disclosed
WO-2014139970-A1 PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT JANSSEN PHARMACEUTICA NV (BE) 2014-09-18 WO disclosed
WO-2014058035-A1 NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2014-04-17 WO disclosed
CN-101208303-A CGRP receptor antagonists MERCK & CO INC (US) 2008-06-25 CN disclosed
WO-2006136917-A1 TRIAZOLYLPIPERIDINE DERIVATIVES AND USE THEREOF IN THERAPY PFIZER LIMITED (GB) 2006-12-28 WO disclosed