Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.71 |
| ▸ | CNR1 | P21554 | 5/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809664 | 0.88 | CNR2 (0.56) | CNR2CNR1SMN1; SMN2GAA | |
| SCHEMBL13871396 | 0.88 | CNR2 (0.59) | CNR2CNR1HTTNPSR1MAPT | |
| SCHEMBL5806477 | 0.83 | CNR2 (0.48) | CNR2CNR1HTTNPSR1MAPT | |
| SCHEMBL5806769 | 0.81 | CNR2 (0.96) | CNR2CNR1 | |
| SCHEMBL5811567 | 0.81 | CYP2C9 (0.48) | CNR2CNR1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5822513 | 0.79 | SMN1; SMN2 (0.48) | CNR2CNR1HTTNPSR1MAPT | |
| SCHEMBL14003108 | 0.77 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL5822464 | 0.76 | CNR2 (0.85) | CNR2CNR1 | |
| SCHEMBL300647 | 0.74 | CNR2 (0.62) | CNR2CNR1ALDH1A1P2RX7 | |
| SCHEMBL13871330 | 0.72 | POLB (0.49) | CNR2CNR1HTTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030124-A1 | CONDENSED PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2006-03-23 | — | — | WO | disclosed |