Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 7/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | PEX14 | O75381 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807508 | 0.87 | MAPT (0.46) | LMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL182893 | 0.85 | FABP4 (0.49) | LMNAGAAPOLBKCNK3SIGMAR1 | |
| SCHEMBL2870198 | 0.84 | PTGER4 (0.48) | LMNAMAPTSMN1; SMN2SIGMAR1 | |
| SCHEMBL2843685 | 0.84 | PTGER4 (0.48) | LMNAMAPTSMN1; SMN2SIGMAR1 | |
| SCHEMBL300478 | 0.84 | FABP4 (0.50) | GAAPOLBKCNK3SIGMAR1 | |
| SCHEMBL5806383 | 0.83 | FABP4 (0.49) | CYP2C9LMNAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5822513 | 0.83 | SMN1; SMN2 (0.48) | LMNAMAPTRAB9ASMN1; SMN2GAA | |
| SCHEMBL4218086 | 0.82 | FABP4 (0.50) | LMNASMN1; SMN2KCNK3SIGMAR1 | |
| SCHEMBL5811340 | 0.81 | CNR2 (0.71) | LMNAMAPTSMN1; SMN2GAACNR1 | |
| SCHEMBL5806477 | 0.79 | CNR2 (0.48) | LMNAMAPTRAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030124-A1 | CONDENSED PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2006-03-23 | — | — | WO | disclosed |