Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5807377 | 0.99 | PDE3A (0.46) | PDE3AGBA1GSK3BPRKDCDRD2 | |
| SCHEMBL5795860 | 0.86 | DRD2 (0.48) | PDE3AGBA1GSK3BPRKDCDRD2 | |
| SCHEMBL5809775 | 0.86 | PDE3A (0.45) | PDE3AGBA1GSK3BPRKDCDRD2 | |
| Hydrochloric Acid SCHEMBL5806331 | 0.86 | DRD2 (0.47) | PDE3AGBA1GSK3BPRKDCDRD2 | |
| Hydrochloric Acid SCHEMBL5809323 | 0.85 | PDE3A (0.44) | PDE3AGBA1GSK3BPRKDCDRD2 | |
| SCHEMBL5805404 | 0.84 | PDE3A (0.43) | PDE3AGBA1GSK3BPRKDCDRD2 | |
| SCHEMBL5809995 | 0.84 | PDE3A (0.43) | PDE3AGBA1PRKDCDRD2DRD1 | |
| Hydrochloric Acid SCHEMBL5809017 | 0.84 | PDE3A (0.41) | PDE3AGBA1PRKDCDRD2DRD1 | |
| Hydrochloric Acid SCHEMBL5808790 | 0.83 | PDE3A (0.43) | PDE3AGBA1PRKDCDRD2DRD1 | |
| Hydrochloric Acid SCHEMBL5811717 | 0.83 | PDE3A (0.45) | PDE3AGBA1GSK3BPRKDCDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |