Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443963 | 0.86 | HDAC1 (0.60) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL6821030 | 0.80 | HDAC1 (0.62) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL30049411 | 0.80 | HDAC1 (0.62) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL28900325 | 0.78 | CYP19A1 (0.58) | HDAC1HDAC6SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL18002299 | 0.74 | HTR6 (0.51) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL6086266 | 0.73 | HDAC1 (0.62) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL4057306 | 0.73 | HDAC1 (0.58) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL20853225 | 0.73 | HDAC1 (0.62) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL3630589 | 0.73 | MEN1 (0.42) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL2826918 | 0.72 | FGFR1 (0.47) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |