Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815362 | 0.99 | KMT2A (0.61) | KMT2AALDH1A1CYP1A2HSD17B10PTGS2 | |
| SCHEMBL5822733 | 0.93 | KMT2A (0.51) | KMT2AALDH1A1CYP1A2PTGS2TSHR | |
| SCHEMBL5822933 | 0.93 | KMT2A (0.51) | KMT2AALDH1A1CYP1A2PTGS2TSHR | |
| SCHEMBL5817700 | 0.90 | KMT2A (0.48) | KMT2AALDH1A1CYP1A2HSD17B10TSHR | |
| SCHEMBL5813372 | 0.90 | KMT2A (0.52) | KMT2AALDH1A1CYP1A2HSD17B10PTGS2 | |
| SCHEMBL5819016 | 0.89 | KMT2A (0.46) | KMT2AALDH1A1CYP1A2HSD17B10CYP2C9 | |
| SCHEMBL5818863 | 0.87 | KMT2A (0.51) | KMT2AALDH1A1CYP1A2HSD17B10PTGS2 | |
| SCHEMBL5817154 | 0.86 | KMT2A (0.50) | KMT2AALDH1A1CYP1A2HSD17B10TSHR | |
| SCHEMBL5818510 | 0.83 | KMT2A (0.39) | KMT2AALDH1A1MEN1CYP2C9KDM4E | |
| SCHEMBL5823115 | 0.82 | KMT2A (0.39) | KMT2AALDH1A1MEN1CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |