Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.40 |
| ▸ | USP2 | O75604 | 6/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.40 |
| ▸ | CASP1 | P29466 | 6/20 | 0.40 |
| ▸ | CASP7 | P55210 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5817700 | 0.96 | KMT2A (0.48) | KMT2AALDH1A1CYP1A2USP2HIF1A | |
| SCHEMBL5813372 | 0.91 | KMT2A (0.52) | KMT2AALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL5818863 | 0.90 | KMT2A (0.51) | KMT2AALDH1A1CYP1A2CYP3A4HPGD | |
| SCHEMBL5822933 | 0.88 | KMT2A (0.51) | KMT2AALDH1A1CYP1A2HPGDCYP2C9 | |
| SCHEMBL5822733 | 0.88 | KMT2A (0.51) | KMT2AALDH1A1CYP1A2HPGDCYP2C9 | |
| SCHEMBL5823265 | 0.88 | KCNH2 (0.44) | KMT2AALDH1A1CYP1A2USP2HIF1A | |
| SCHEMBL5812232 | 0.86 | KMT2A (0.62) | KMT2AALDH1A1CYP1A2USP2HIF1A | |
| SCHEMBL5815362 | 0.85 | KMT2A (0.61) | KMT2AALDH1A1CYP1A2USP2HIF1A | |
| SCHEMBL5814697 | 0.84 | MEN1 (0.38) | KMT2AALDH1A1HTR2BMAPTKDM4E | |
| SCHEMBL5823482 | 0.83 | KCNH2 (0.44) | ALDH1A1CYP1A2USP2HIF1ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |