Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560509 | 0.91 | PTGS2 (0.42) | MEN1KMT2AAKR1C3AKR1C2SRC | |
| SCHEMBL5560592 | 0.91 | PTGS2 (0.42) | MEN1KMT2AAKR1C3AKR1C2SRC | |
| SCHEMBL5550416 | 0.91 | PTGS2 (0.42) | MEN1KMT2AAKR1C3AKR1C2SRC | |
| SCHEMBL5560432 | 0.88 | AKR1C3 (0.36) | MEN1KMT2AAKR1C3AKR1C2SRC | |
| SCHEMBL6424980 | 0.88 | PTGS2 (0.35) | MEN1KMT2AAKR1C3AKR1C2SRC | |
| SCHEMBL6424935 | 0.87 | AKR1C3 (0.36) | MEN1KMT2AAKR1C3AKR1C2SRC | |
| SCHEMBL6425967 | 0.87 | AKR1C3 (0.36) | MEN1KMT2AAKR1C3AKR1C2SRC | |
| SCHEMBL6425546 | 0.87 | MEN1 (0.34) | MEN1KMT2AAKR1C3AKR1C2SRC | |
| SCHEMBL5560568 | 0.85 | MEN1 (0.36) | MEN1KMT2AAKR1C3AKR1C2SRC | |
| SCHEMBL5560569 | 0.85 | MEN1 (0.36) | MEN1KMT2AAKR1C3AKR1C2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |