Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.45 |
| ▸ | PPARA | Q07869 | 15/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812690 | 1.00 | PPARG (0.45) | PPARGPPARAKDM4EALDH1A1TP53 | |
| SCHEMBL5802258 | 0.96 | PPARG (0.49) | PPARGPPARAKDM4EALDH1A1TP53 | |
| SCHEMBL5809174 | 0.93 | PPARA (0.49) | PPARGPPARA | |
| SCHEMBL5809170 | 0.93 | PPARA (0.49) | PPARGPPARA | |
| SCHEMBL5809552 | 0.92 | PPARG (0.38) | PPARGPPARAKDM4EALDH1A1TP53 | |
| SCHEMBL5809549 | 0.92 | PPARG (0.38) | PPARGPPARAKDM4EALDH1A1TP53 | |
| SCHEMBL5798063 | 0.89 | PPARA (0.51) | PPARGPPARA | |
| SCHEMBL5798061 | 0.89 | PPARA (0.51) | PPARGPPARA | |
| SCHEMBL5813522 | 0.88 | POLB (0.46) | PPARGPPARAKDM4EALDH1A1TP53 | |
| SCHEMBL5813524 | 0.88 | POLB (0.46) | PPARGPPARAKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |