Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.38 |
| ▸ | PPARA | Q07869 | 12/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809549 | 1.00 | PPARG (0.38) | PPARGPPARAMAPTTSHRALOX15 | |
| SCHEMBL5812488 | 0.96 | PPARG (0.40) | PPARGPPARAMAPTTSHRALOX15 | |
| SCHEMBL5813503 | 0.93 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL5813501 | 0.93 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL5812693 | 0.92 | PPARG (0.45) | PPARGPPARAMAPTKDM4EALDH1A1 | |
| SCHEMBL5812690 | 0.92 | PPARG (0.45) | PPARGPPARAMAPTKDM4EALDH1A1 | |
| SCHEMBL5814610 | 0.89 | PPARG (0.46) | PPARGPPARATSHRKDM4EMAPK1 | |
| SCHEMBL5814614 | 0.89 | PPARG (0.46) | PPARGPPARATSHRKDM4EMAPK1 | |
| SCHEMBL5815262 | 0.88 | POLB (0.41) | PPARGPPARAMAPTTSHRALOX15 | |
| SCHEMBL5815263 | 0.88 | POLB (0.41) | PPARGPPARAMAPTTSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |