Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CCND3 | P30281 | 2/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5818977 | 0.93 | MAPK9 (0.50) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5819878 | 0.93 | PRKD1 (0.49) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5816128 | 0.93 | MAPK14 (0.49) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5813677 | 0.93 | KCNH2 (0.49) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5818802 | 0.93 | MAPK13 (0.50) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5815108 | 0.89 | KCNH2 (0.49) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5818729 | 0.89 | MAPK14 (0.51) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5818908 | 0.89 | MAPK14 (0.49) | MAPK13MAPK12MAPK11MAPK14MAPK9 | |
| SCHEMBL5812981 | 0.89 | BRAF (0.50) | MAPK13MAPK12MAPK11MAPK14KCNH2 | |
| SCHEMBL5813428 | 0.89 | BRAF (0.50) | MAPK13MAPK12MAPK11MAPK14KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |