Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5558975 | 0.93 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL5554078 | 0.93 | PTGS2 (0.68) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5809345 | 0.89 | PTGS2 (0.59) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5559201 | 0.88 | PTGS2 (0.65) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5814794 | 0.88 | PTGS2 (0.70) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5559939 | 0.86 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL5555588 | 0.86 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL5558185 | 0.86 | PTGS2 (0.70) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5559182 | 0.86 | PTGS2 (0.77) | PTGS2PTGS1HRH4HDAC3HDAC1 | |
| SCHEMBL5813394 | 0.86 | PTGS2 (0.61) | PTGS2PTGS1HRH4HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |