Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | IKBKB | O14920 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812763 | 0.96 | KMT2A (0.61) | KMT2AIKBKBHTR6HRH4KCNH2 | |
| SCHEMBL5818777 | 0.95 | KMT2A (0.60) | KMT2AIKBKBHTR6HRH4KCNH2 | |
| SCHEMBL5818512 | 0.91 | KMT2A (0.50) | KMT2AIKBKBKCNH2ALDH1A1EGFR | |
| SCHEMBL5816363 | 0.90 | KCNH2 (0.53) | KMT2AIKBKBKCNH2EGFRACHE | |
| SCHEMBL5815226 | 0.89 | KMT2A (0.50) | KMT2AIKBKBHTR6HRH4KCNH2 | |
| SCHEMBL5814477 | 0.89 | KCNH2 (0.55) | IKBKBKCNH2EGFR | |
| SCHEMBL5813351 | 0.87 | KMT2A (0.48) | KMT2AIKBKBHTR6HRH4KCNH2 | |
| SCHEMBL5819339 | 0.86 | KMT2A (0.48) | KMT2AIKBKBHTR6HRH4KCNH2 | |
| SCHEMBL5817757 | 0.86 | KCNH2 (0.53) | KMT2AIKBKBKCNH2 | |
| SCHEMBL5813636 | 0.86 | ALDH1A1 (0.48) | KMT2AKDM4EMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |