SCHEMBL581352

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Enzalutamide SCHEMBL189749	0.91	AR (1.00)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL21788386	0.91	AR (0.87)	ARGABRPGABRDNR1I2NR3C1
	Enzalutamide SCHEMBL29352764	0.91	AR (1.00)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL23378228	0.91	AR (0.85)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL26158840	0.90	AR (0.68)	ARGABRPGABRDNR1I2NR3C1
	Deutenzalutamide SCHEMBL29692768	0.89	AR (0.89)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL22675177	0.89	AR (0.83)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL20465765	0.89	AR (0.83)	ARGABRPGABRDNR1I2NR3C1
	Deutenzalutamide SCHEMBL18789402	0.89	AR (0.89)	ARGABRPGABRDNR1I2NR3C1
	SCHEMBL22197966	0.89	AR (0.75)	ARGABRPGABRDNR1I2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.