TUBB6

Tubulin beta-6 chain · Q9BUF5 · TUBB6 on Sugi Atlas →

132,792 patent compounds predicted against TUBB6, 83,971 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Curacin A Curacin A (SCHEMBL61304) 1.00 20/20
Vintriptol Vintriptol (SCHEMBL93959) 1.00 15/20
Vindesine Vindesine (SCHEMBL4420) 0.85 13/20
Vindesine Vindesine (SCHEMBL4421) 0.85 13/20
Vindesine Vindesine (SCHEMBL4285) 0.85 12/20
SCHEMBL147173 SCHEMBL147173 0.50 12/20
SCHEMBL147174 SCHEMBL147174 0.50 12/20
Combretastatin Combretastatin (SCHEMBL19955) 1.00 9/20
Combretastatin Combretastatin (SCHEMBL19956) 1.00 9/20
SCHEMBL118593 SCHEMBL118593 0.69 9/20
Centaureidin Centaureidin (SCHEMBL9953) 1.00 8/20
Thiocolchicine Thiocolchicine (SCHEMBL43160) 1.00 8/20
Thiocolchicine Thiocolchicine (SCHEMBL43161) 1.00 8/20
SCHEMBL68067 SCHEMBL68067 0.62 8/20
Fosbretabulin Fosbretabulin (SCHEMBL66079) 0.61 8/20
Vinorelbine Vinorelbine (SCHEMBL4765) 1.00 7/20
Combretastatin A4 Combretastatin A4 (SCHEMBL18945) 1.00 7/20
Combretastatin A4 Combretastatin A4 (SCHEMBL18946) 1.00 7/20
Levofloxacin Anhydrous Levofloxacin Anhydrous (SCHEMBL15397) 0.98 7/20
Ofloxacin Ofloxacin (SCHEMBL24373) 0.98 7/20

Clinical trials — most relevant to TUBB6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Paclitaxel, Nab-paclitaxel, or Ixabepilone With or Without Bevacizumab in Treating Patients With Stage IIIC or Stage IV Breast Cancer PHASE3COMPLETED
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Biologic Correlative Taxotere/AC PHASE2COMPLETED
Vinorelbine in Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer PHASE2UNKNOWN
First-line Gemcitabine Plus Cisplatin in Locally Advanced (IIIC Stage) Breast Cancer Patients PHASE2ACTIVE_NOT_RECRUITING
A Multicenter Study of NAP (AL-108) in Schizophrenia PHASE2COMPLETED
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer PHASE2COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies PHASE1COMPLETED
Treating Patients With Advanced Solid Tumors, Breast Cancer or Recurrent Ovarian Cancer PHASE1COMPLETED
SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromes PHASE1COMPLETED
Far Infrared Irradiation for the Management, Control and Treatment of Frontotemporal Dementia PHASE1UNKNOWN
Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer PHASE1ACTIVE_NOT_RECRUITING
Exploratory Evaluation of [11C]MPC6827 EARLY_PHASE1COMPLETED
Diagnostic of Chemotherapy Induced Neuropathy in Children nanCOMPLETED
Prostate Cancer Antigen 3 (PCA-3) Gene Project nanCOMPLETED
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
Effect of Low Dose of Colchicine on Platelet Reactivity nanCOMPLETED
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
The Relation of Microtubule-Associated Protein 2 and Cell Migration nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting nanUNKNOWN
Autophagy Bladder Cancer nanUNKNOWN
WGS of Korean Idiopathic Bronchiectasis nanUNKNOWN
Myotubular Myopathy Genetic Testing Study nanCOMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
PCD New Gene Discovery nanCOMPLETED
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
Biomarkers in the Diagnosis and Prognosis of NAFLD nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a TUBB6 binder may also engage these)

ProteinNameSimilarity
Q2HJ81 1.000 Q2HJ81 →
Q6B856 1.000 Q6B856 →
P85108 1.000 P85108 →
TUBB2A Tubulin beta-2A chain 1.000 landscape →
TUBB2B Tubulin beta-2B chain 1.000 landscape →
P46265 1.000 P46265 →
Q4R4X8 1.000 Q4R4X8 →
Q3MHM5 1.000 Q3MHM5 →
P68372 1.000 P68372 →
P11833 1.000 P11833 →
P69893 1.000 P69893 →
Q6GLE7 1.000 Q6GLE7 →
Q27U48 1.000 Q27U48 →
P12456 1.000 P12456 →
O44388 1.000 O44388 →
P02554 1.000 P02554 →
Q24560 1.000 Q24560 →
O59837 1.000 O59837 →
P30883 1.000 P30883 →
P09652 1.000 P09652 →
Q9D6F9 1.000 Q9D6F9 →
P61858 1.000 P61858 →
Q3ZBU7 1.000 Q3ZBU7 →
P14140 1.000 P14140 →
P33127 1.000 P33127 →
Q5R943 1.000 Q5R943 →
Q17299 1.000 Q17299 →
Q91240 1.000 Q91240 →
P09653 1.000 P09653 →
P41937 1.000 P41937 →