Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.46 |
| ▸ | BCL2 | P10415 | 3/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813622 | 1.00 | TDP1 (0.48) | TDP1HRH3HTR2AHTR7HTR6 | |
| SCHEMBL5796248 | 0.89 | TDP1 (0.46) | TDP1HRH3HTR2AHTR7HTR6 | |
| SCHEMBL5796244 | 0.89 | TDP1 (0.46) | TDP1HRH3HTR2AHTR7HTR6 | |
| SCHEMBL5799039 | 0.87 | PRMT5 (0.47) | MCL1BCL2P2RX3PIN1BCL2L1 | |
| SCHEMBL5807171 | 0.87 | PRMT5 (0.47) | MCL1BCL2P2RX3PIN1BCL2L1 | |
| SCHEMBL5808364 | 0.84 | PIN1 (0.46) | TDP1MCL1BCL2P2RX3PIN1 | |
| SCHEMBL5808367 | 0.84 | PIN1 (0.46) | TDP1MCL1BCL2P2RX3PIN1 | |
| SCHEMBL5813909 | 0.83 | PIN1 (0.45) | TDP1MCL1BCL2P2RX3PIN1 | |
| SCHEMBL5813912 | 0.83 | PIN1 (0.45) | TDP1MCL1BCL2P2RX3PIN1 | |
| SCHEMBL5823776 | 0.81 | PIN1 (0.42) | TDP1MCL1BCL2P2RX3PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |