Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | HCK | P08631 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12043978 | 0.88 | PIK3CD (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL1054326 | 0.79 | SIGMAR1 (0.43) | AKT1PIK3CDABL1EGFRHCK | |
| SCHEMBL10820368 | 0.78 | OXER1 (0.48) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL1057433 | 0.78 | PIK3CD (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL29658586 | 0.78 | PIK3CD (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL1058348 | 0.77 | PIK3CD (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL29433057 | 0.77 | PIK3CD (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL16756072 | 0.77 | NR1H2 (0.52) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL10819613 | 0.77 | PIK3CD (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL13167710 | 0.77 | PIK3CD (0.44) | PIK3CDABL1EGFRHCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707566-A1 | Deazapurines and uses thereof | Eisai Co., Ltd. (JP) | 2006-10-04 | — | — | EP | disclosed |