Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCND3 | P30281 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | MMP7 | P09237 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819436 | 0.99 | ALDH1A1 (0.43) | ALDH1A1DYRK1AGPR119DYRK2HTT | |
| SCHEMBL5814237 | 0.97 | ALDH1A1 (0.45) | ALDH1A1DYRK1AGPR119DYRK2HTT | |
| SCHEMBL5813784 | 0.92 | DYRK2 (0.43) | DYRK2SYKALOX5CDK1CDK4 | |
| SCHEMBL5818721 | 0.91 | DYRK2 (0.43) | DYRK2SYKALOX5CDK1CDK4 | |
| SCHEMBL5817914 | 0.89 | PRKD3 (0.44) | DYRK2SYKCDK2 | |
| SCHEMBL5819839 | 0.87 | MAPK14 (0.42) | GPR119DYRK2SYKCDK1CDK4 | |
| SCHEMBL5819371 | 0.87 | IKBKB (0.43) | ALDH1A1CDK1CDK4CCNB1CCNA2 | |
| SCHEMBL5819074 | 0.87 | ALDH1A1 (0.47) | ALDH1A1DYRK1AGPR119DYRK2HTT | |
| SCHEMBL5818643 | 0.86 | MAPK14 (0.41) | GPR119DYRK2SYKCDK1CDK4 | |
| SCHEMBL5819127 | 0.86 | BRAF (0.44) | DYRK2SYKCDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |