Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 5/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5816324 | 0.87 | BRAF (0.49) | KDM4ETP53MAPTCCNA2CDK2 | |
| SCHEMBL5811808 | 0.86 | BRAF (0.48) | MAPK9TP53MAPTCCNA2CDK2 | |
| SCHEMBL5813771 | 0.85 | MAPK14 (0.50) | KDM4ECCNA2CDK2MAPK3MAPK1 | |
| SCHEMBL5823374 | 0.85 | ADORA1 (0.53) | MAPK9CCNA2CDK2MAPK3MAPK1 | |
| SCHEMBL5819449 | 0.84 | ADORA1 (0.52) | MAPK9CSNK1DCCNA2CDK2MAPK3 | |
| SCHEMBL5818867 | 0.84 | MAPK14 (0.49) | KDM4ECCNA2CDK2MAPK14PIM1 | |
| SCHEMBL5813505 | 0.83 | BRAF (0.52) | MAPK9CCNA2CDK2MAPK3MAPK1 | |
| SCHEMBL5812949 | 0.81 | MAPK13 (0.46) | MAPK9CSNK1A1CSNK1DRPS6KA3KDM4E | |
| SCHEMBL5814670 | 0.81 | ADORA1 (0.47) | MAPK9CCNA2CDK2MAPK3MAPK1 | |
| SCHEMBL5813443 | 0.81 | MAPK14 (0.45) | MAPK9CCNA2CDK2MAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |