Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.46 |
| ▸ | PPARA | Q07869 | 15/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5814614 | 1.00 | PPARG (0.46) | PPARGPPARATSHRMAPK1KDM4E | |
| SCHEMBL5813501 | 0.95 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL5813503 | 0.95 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL5812488 | 0.93 | PPARG (0.40) | PPARGPPARATSHRMAPK1KDM4E | |
| SCHEMBL5814061 | 0.92 | PPARG (0.46) | PPARGPPARAKDM4E | |
| SCHEMBL5814066 | 0.92 | PPARG (0.46) | PPARGPPARAKDM4E | |
| SCHEMBL5798063 | 0.91 | PPARA (0.51) | PPARGPPARA | |
| SCHEMBL5798061 | 0.91 | PPARA (0.51) | PPARGPPARA | |
| SCHEMBL5809549 | 0.89 | PPARG (0.38) | PPARGPPARATSHRMAPK1KDM4E | |
| SCHEMBL5809552 | 0.89 | PPARG (0.38) | PPARGPPARATSHRMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | claimed |
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |