Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 16/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 16/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 16/20 | 0.54 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819183 | 0.92 | MAPK14 (0.54) | MAPK14MAPK13MAPK12MAPK11CAMK2D | |
| SCHEMBL5819268 | 0.92 | MAPK13 (0.55) | MAPK14MAPK13MAPK12MAPK11CAMK2D | |
| SCHEMBL5818817 | 0.91 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11CAMK2D | |
| SCHEMBL5813688 | 0.91 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11CAMK2D | |
| SCHEMBL5813695 | 0.91 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11CAMK2D | |
| SCHEMBL5823067 | 0.91 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11CAMK2D | |
| SCHEMBL5814407 | 0.86 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5819690 | 0.84 | ALDH1A1 (0.49) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5819797 | 0.82 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11MAPK9 | |
| SCHEMBL5820847 | 0.82 | MAPK13 (0.54) | MAPK14MAPK13MAPK12MAPK11CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |