Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25274260 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KMT2ANPSR1HTTNPC1 | |
| SCHEMBL9640442 | 0.85 | NPC1 (0.70) | ALDH1A1KMT2ANPSR1HTTNPC1 | |
| SCHEMBL5814863 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2ANPSR1HTTNPC1 | |
| SCHEMBL14202796 | 0.82 | ALDH1A1 (0.63) | ALDH1A1KMT2ANPSR1HTTNPC1 | |
| SCHEMBL28215851 | 0.81 | KMT2A (0.53) | ALDH1A1KMT2ANPSR1HTTNPC1 | |
| SCHEMBL11224556 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KMT2ANPSR1HTTNPC1 | |
| SCHEMBL2097502 | 0.80 | NPSR1 (0.50) | ALDH1A1KMT2ANPSR1HTTNPC1 | |
| SCHEMBL2097499 | 0.79 | NPSR1 (0.48) | ALDH1A1KMT2ANPSR1HTTNPC1 | |
| SCHEMBL30596237 | 0.75 | NPSR1 (0.44) | ALDH1A1KMT2ANPSR1HTTNPC1 | |
| SCHEMBL1031457 | 0.71 | NPC1 (0.50) | ALDH1A1KMT2ANPSR1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |