Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 14/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115928 | 0.96 | PRKCI (0.46) | PRKCICHRM4MAPTGAANPSR1 | |
| SCHEMBL7513678 | 0.95 | MAPT (0.44) | PRKCICHRM4MAPTGAANPSR1 | |
| SCHEMBL5128775 | 0.91 | MAPT (0.47) | PRKCICHRM4MAPTGAANPSR1 | |
| SCHEMBL7171668 | 0.90 | MAPT (0.51) | CHRM4MAPTGAANPSR1DYRK1A | |
| SCHEMBL7615852 | 0.88 | PRKCI (0.49) | PRKCI | |
| SCHEMBL5809171 | 0.87 | PRKCI (0.48) | PRKCI | |
| SCHEMBL5123014 | 0.87 | PRKCI (0.58) | PRKCICHRM4MAPTGAANPSR1 | |
| SCHEMBL5814433 | 0.87 | CHRM4 (0.39) | CHRM4MAPTNPSR1CLK1CLK2 | |
| SCHEMBL5814655 | 0.86 | CHRM4 (0.40) | CHRM4MAPTNPSR1CLK1CLK2 | |
| SCHEMBL5809738 | 0.86 | PRKCI (0.46) | PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685136-A1 | USE OF THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047292-A1 | USE OF THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 2005-05-26 | — | — | WO | disclosed |
| EP-0920431-A1 | THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006722-A1 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |