Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 19/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5129890 | 0.96 | PRKCI (0.51) | PRKCIADORA2AADORA1 | |
| SCHEMBL7506325 | 0.90 | PRKCI (0.58) | PRKCIADORA2AADORA1 | |
| SCHEMBL7176188 | 0.89 | ALDH1A1 (0.52) | — | |
| SCHEMBL5121254 | 0.88 | PRKCI (0.62) | PRKCIADORA2AADORA1 | |
| SCHEMBL5815092 | 0.87 | PRKCI (0.43) | PRKCI | |
| SCHEMBL5813871 | 0.87 | MEN1 (0.46) | PRKCI | |
| SCHEMBL5130858 | 0.86 | PRKCI (0.47) | PRKCI | |
| SCHEMBL7513678 | 0.86 | MAPT (0.44) | PRKCI | |
| SCHEMBL5123238 | 0.85 | CLK4 (0.54) | — | |
| SCHEMBL7516123 | 0.84 | USP1 (0.34) | PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685136-A1 | USE OF THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047292-A1 | USE OF THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 2005-05-26 | — | — | WO | disclosed |