Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.48 |
| ▸ | PPARA | Q07869 | 17/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815267 | 1.00 | PPARG (0.48) | PPARGPPARAPOLBKDM4EPPARD | |
| SCHEMBL5814061 | 0.95 | PPARG (0.46) | PPARGPPARAPOLBKDM4E | |
| SCHEMBL5814066 | 0.95 | PPARG (0.46) | PPARGPPARAPOLBKDM4E | |
| SCHEMBL5810162 | 0.93 | POLB (0.41) | PPARGPPARAPOLBKDM4E | |
| SCHEMBL5814678 | 0.93 | PPARG (0.48) | PPARGPPARAPPARD | |
| SCHEMBL5810168 | 0.93 | POLB (0.41) | PPARGPPARAPOLBKDM4E | |
| SCHEMBL5814681 | 0.93 | PPARG (0.48) | PPARGPPARAPPARD | |
| SCHEMBL5815227 | 0.90 | PPARA (0.49) | PPARGPPARAPOLBPPARD | |
| SCHEMBL5815263 | 0.88 | POLB (0.41) | PPARGPPARAPOLBKDM4E | |
| SCHEMBL5815262 | 0.88 | POLB (0.41) | PPARGPPARAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |